Completed Projects
1
Care and outcomes of Canadian children hospitalized with periorbital and orbital cellulitis
Severe orbital infections, including periorbital and orbital cellulitis, are serious infections in children. There are several important unanswered research questions regarding how hospitalized children with these infections are managed, such as which antibiotics to use, and which children need a computed tomography (CT) scan. PIRN is conducting a retrospective study across 10 hospitals to determine how care for Canadian children can be improved.
2
Paediatric Hospital Care Priority Setting Study
PIRN, in collaboration with the James Lind Alliance (JLA), conducted a CIHR-funded Priority Setting Partnership (PSP) to identify the Top 10 research questions for Inpatient General Paediatrics in Canada from the perspective of patients, caregivers, and clinicians. These priorities will guide the future research agenda for hospitalized children in Canada, and include care of special inpatient populations (eg, children with medical complexity), shared decision-making, mental health supports, and supporting Indigenous families. Funding Source: CIHR Catalyst Grant in Patient Oriented Research PIRN is conducting a national, prospective, pragmatic, observational study across 15 hospitals to generate knowledge on shared decision making with parents in choosing between IV and NG fluids and on the benefits and harms of these two treatment options for hospitalized children with bronchiolitis. Funding Source: CIHR Patient-Oriented Research: Early-Career Investigator Priority Announcement
3
Description of Canadian infants presenting with Brief Resolved Unexplained Events (BRUEs) and validation of a clinical prediction rule for risk stratification
Infants often experience Brief Resolved Unexplained Events (BRUEs) within the first year of life. These events are concerning for caregivers, can appear to be life-threatening and pose diagnostic and management challenges for healthcare providers as they attempt to identify events likely to recur, or those caused by a serious underlying illness. Although studies have been conducted to develop clinical practice guidelines and clinical prediction rules in the United States, no studies to date have assessed the BRUE population in Canada. PIRN will conduct a multi-site retrospective observational study of hospitalized children in Canada to identify variation in the clinical management of infants presenting with BRUEs, inform practitioners and improve outcomes. Funding Sources: American Academy of Pediatrics – Resident Research Grant Program; BC Children’s Hospital – BCCH Resident Research Funding; BC Children's Hospital Research Institute (E2i) – Seeds Grant (Early Investigator) and Canadian Pediatric Society (CPS) – Hospital Pediatrics Resident Grant